Hi! I am a first year internal medicine resident in the Stanbury Physician-Scientist Pathway at Massachusetts General Hospital. I recently obtained my MD and PhD through the Medical Scientist Training Program at Harvard Medical School and MIT. My PhD was completed in the Medical Engineering and Medical Physics program under the supervision of Matthew Vander Heiden. There, I used small molecule and genetic approaches to understand how metabolism and DNA replication fidelity affect cell fate decisions in the hematopoietic system.

I completed my undergradute degree at Stanford University in biology and computer science. I was advised by Howard Chang, where I studied noncoding RNAs and their structure, interactions, and function. We discovered how these RNAs orchestrate gene regulation, cell fate, and many other processes through noncanonical functions. Previously, I worked with Long-Cheng Li at UCSF on small RNA-mediated gene activation in the worm C. elegans.

I'm also excited by the role of technology in healthcare and other industries. During summer 2015, I interned at Flatiron Health as a Data Insights Engineer, where I helped build analytics tools on top of a million-patient clinicogenomic database that will be used for drug discovery and personalized medicine.

In my free time I love running, sailing, biking, and baking. I follow college football pretty avidly and enjoy learning new skills, whether it's a new instrument, programming language, or sport. Finally, I love tacos. Contact me if you know of a great taco place.

Email me at brian_do at mit dot edu.